Peng, Hong-Shang and Huang, Shi-Hua and Wolfbeis, Otto S. (2010) Ratiometric fluorescent nanoparticles for sensing temperature. Journal of Nanoparticle Research, 12 (8). pp. 2729-2733.
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A ratiometric type of fluorescent nanoparticle was prepared via an encapsulation–reprecipitation method. By introducing an alkoxysilanized dye as a reference, the nanoparticles (NPs) give both a green and a red fluorescence under one single-wavelength excitation. The resulted ratiometric fluorescence is found to be highly temperature-dependent in the physiological range (25–45 °C), with an intensity temperature sensitivity of −4.0%/°C. Given the small size (20–30 nm in diameter) and biocompatible nature (silica out layer), such kind of NPs were very promising as temperature nanosensors for cellular sensing and imaging.
|Uncontrolled Keywords:||Ratiometric fluorescence - Nanoparticles - Europium chelate - Temperature sensing|
|Subjects:||Material Science > Nanochemistry|
|Deposited On:||14 Jan 2011 07:28|
|Last Modified:||14 Jan 2011 07:28|
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