Nano Archive

Ratiometric fluorescent nanoparticles for sensing temperature

Peng, Hong-Shang and Huang, Shi-Hua and Wolfbeis, Otto S. (2010) Ratiometric fluorescent nanoparticles for sensing temperature. Journal of Nanoparticle Research, 12 (8). pp. 2729-2733.

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A ratiometric type of fluorescent nanoparticle was prepared via an encapsulation–reprecipitation method. By introducing an alkoxysilanized dye as a reference, the nanoparticles (NPs) give both a green and a red fluorescence under one single-wavelength excitation. The resulted ratiometric fluorescence is found to be highly temperature-dependent in the physiological range (25–45 °C), with an intensity temperature sensitivity of −4.0%/°C. Given the small size (20–30 nm in diameter) and biocompatible nature (silica out layer), such kind of NPs were very promising as temperature nanosensors for cellular sensing and imaging.

Item Type:Article
Uncontrolled Keywords:Ratiometric fluorescence - Nanoparticles - Europium chelate - Temperature sensing
Subjects:Material Science > Nanochemistry
ID Code:9949
Deposited By:CSMNT
Deposited On:14 Jan 2011 07:28
Last Modified:14 Jan 2011 07:28

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