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Synthesis of Bio-Compatible SPION–based Aqueous Ferrofluids and Evaluation of RadioFrequency Power Loss for Magnetic Hyperthermia

Reena Mary, A. P. and Narayanan, T. N. and Sunny, Vijutha and Sakthikumar, D. and Yoshida, Yasuhiko and Joy, P. A. and Anantharaman, M. R. (2010) Synthesis of Bio-Compatible SPION–based Aqueous Ferrofluids and Evaluation of RadioFrequency Power Loss for Magnetic Hyperthermia. Nanoscale Research Letters, 5 (10). pp. 1706-1711.

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Abstract

Bio-compatible magnetic fluids having high saturation magnetization find immense applications in various biomedical fields. Aqueous ferrofluids of superparamagnetic iron oxide nanoparticles with narrow size distribution, high shelf life and good stability is realized by controlled chemical co-precipitation process. The crystal structure is verified by X-ray diffraction technique. Particle sizes are evaluated by employing Transmission electron microscopy. Room temperature and low-temperature magnetic measurements were carried out with Superconducting Quantum Interference Device. The fluid exhibits good magnetic response even at very high dilution (6.28 mg/cc). This is an advantage for biomedical applications, since only a small amount of iron is to be metabolised by body organs. Magnetic field induced transmission measurements carried out at photon energy of diode laser (670 nm) exhibited excellent linear dichroism. Based on the structural and magnetic measurements, the power loss for the magnetic nanoparticles under study is evaluated over a range of radiofrequencies.

Item Type:Article
Subjects:Material Science > Nanofabrication processes and tools
ID Code:9845
Deposited By:CSMNT
Deposited On:31 Dec 2010 02:50
Last Modified:31 Dec 2010 02:50

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