Nano Archive

Protein Functionalized Nanodiamond Arrays

Liu, Y. L. and Sun, K. W. (2010) Protein Functionalized Nanodiamond Arrays. NANOSCALE RESEARCH LETTERS, 5 (6). pp. 1045-1050. ISSN 1931-7573 (Print) 1556-276X (Online)

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Various nanoscale elements are currently being explored for bio-applications, such as in bio-images, bio-detection, and bio-sensors. Among them, nanodiamonds possess remarkable features such as low bio-cytotoxicity, good optical property in fluorescent and Raman spectra, and good photostability for bio-applications. In this work, we devise techniques to position functionalized nanodiamonds on self-assembled monolayer (SAMs) arrays adsorbed on silicon and ITO substrates surface using electron beam lithography techniques. The nanodiamond arrays were functionalized with lysozyme to target a certain biomolecule or protein specifically. The optical properties of the nanodiamond-protein complex arrays were characterized by a high throughput confocal microscope. The synthesized nanodiamond-lysozyme complex arrays were found to still retain their functionality in interacting with E. coli.

Item Type:Article
Subjects:Material Science > Functional and hybrid materials
ID Code:9272
Deposited By:M T V
Deposited On:03 Jun 2010 14:54
Last Modified:03 Jun 2010 14:54

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