Nano Archive

Highly bacterial resistant silver nanoparticles: synthesis and antibacterial activities

Chudasama, Bhupendra and Vala, Anjana K. and Andhariya, Nidhi and Mehta, R. V. and Upadhyay, R. V. (2010) Highly bacterial resistant silver nanoparticles: synthesis and antibacterial activities. Journal of Nanoparticle Research, 12 (5). pp. 1677-1685.

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In this article, we describe a simple one-pot rapid synthesis route to produce uniform silver nanoparticles by thermal reduction of AgNO3 using oleylamine as reducing and capping agent. To enhance the dispersal ability of as-synthesized hydrophobic silver nanoparticles in water, while maintaining their unique properties, a facile phase transfer mechanism has been developed using biocompatible block co-polymer pluronic F-127. Formation of silver nanoparticles is confirmed by X-ray diffraction (XRD), transmission electron microscopy (TEM) and UV–vis spectroscopy. Hydrodynamic size and its distribution are obtained from dynamic light scattering (DLS). Hydrodynamic size and size distribution of as-synthesized and phase transferred silver nanoparticles are 8.2 ± 1.5 nm (σ = 18.3%) and 31.1 ± 4.5 nm (σ = 14.5%), respectively. Antimicrobial activities of hydrophilic silver nanoparticles is tested against two Gram positive (Bacillus megaterium and Staphylococcus aureus), and three Gram negative (Escherichia coli, Proteus vulgaris and Shigella sonnei) bacteria. Minimum inhibitory concentration (MIC) values obtained in the present study for the tested microorganisms are found much better than those reported for commercially available antibacterial agents.

Item Type:Article
Uncontrolled Keywords:Silver nanoparticles - Pluronic F-127 - Antibacterial activity - Minimum inhibitory concentration - Nanomedicine
Subjects:Material Science > Nanofabrication processes and tools
Biomedical Science > Nanotechnology for animal health
Biomedical Science > Nanotechnology for human health
Biomedical Science > Nanomedicine
ID Code:9233
Deposited By:SPI
Deposited On:08 Jun 2010 17:34
Last Modified:08 Jun 2010 17:34

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