Nano Archive

A potential tocopherol acetate loaded palm oil esters-in-water nanoemulsions for nanocosmeceuticals.

Brian Sheng Xian, Teo and Mahiran, Basri and Mohd Rezuwan Shah, Zakaria and Abu Bakar, Salleh and Raja Noor Zaliha Raja Abdul, Rahman (2010) A potential tocopherol acetate loaded palm oil esters-in-water nanoemulsions for nanocosmeceuticals. J Nanobiotechnology . ISSN 1477-3155

Full text is not hosted in this archive but may be available via the Official URL, or by requesting a copy from the corresponding author.

Official URL: http://www.jnanobiotechnology.com/content/8/1/4

Abstract

BACKGROUND: Cosmeceuticals are cosmetic-pharmaceutical hybrids intended to enhance health and beauty of the skin. Nanocosmeceuticals use nano-sized system for the delivery of active ingredients to the targeted cells for better penetration. In this work, nanoemulsion from palm oil esters was developed as a delivery system to produce nanocosmeceuticals. The stability of the resulting formulation was tested using various methods. In addition, the effect of components i.e. Vitamin E and Pluronic F-68 on the formulation was also studied. RESULTS: Both vitamin E and Pluronic F-68 were found to co-emulsify and co-stabilized the formulations. The best formulation was found to be the one having the composition of 10% Palm Oil Esters (POEs), 10% vitamin E, 24% Tween 80, 2.4% Pluronic F-68 and 53.6% deionised water. Those compositions are considered to be the best as a nanocosmeceutical product due to the small particle size (94.21 nm), low occurrence of Ostwald ripening and stable at different storing temperatures (5, 25 and 45 degrees C) for four weeks. CONCLUSIONS: Palm oil esters-in-water nanoemulsions loaded with vitamin E was successfully formulated and has the potential for the use as nanocosmeceuticals.

Item Type:Article
Subjects:Biomedical Science > Nanobiotechnology
Material Science > Bio materials
ID Code:9027
Deposited By:CSMNT
Deposited On:09 May 2010 05:35
Last Modified:09 May 2010 05:35

Repository Staff Only: item control page