Ozoemena, Kenneth I. (2009) Metallophthalocyanine Based Carbon Paste Electrodes for the Determination of 2',3'-Dideoxyinosine. Electroanalysis, 21 (14). 1651 -1654.
|PDF (Electroanalysis) - Accepted Version|
Novel electrochemical sensors based on carbon paste impregnated with metallopthalocyanine (MPc, MÂ¼Co, Fe) complexes, have been constructed for the assay of anti-HIV drug 2',3'-dideoxyinosine (didanosine, DDI). Both modified electrodes showed electrocatalytic activity towards the oxidation of dideoxyinosine in phosphate buffer pH 7.4 with a working concentration range of 10-7-10-4 mol/L and a detection limit of 10-7 mol/L magnitude order. The sensor proved to be highly reliable for the assay of the purity of DDI - raw material as well as for the uniformity content test of Videx tablets.
|Subjects:||Material Science > Nanochemistry|
|Deposited By:||Mr Saleh Khamlich|
|Deposited On:||15 Jul 2010 10:23|
|Last Modified:||15 Jul 2010 10:23|
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