Nano Archive

CdTe Quantum Dot/Dye Hybrid System as Photosensitizer for Photodynamic Therapy

Rakovich, Aliaksandra and Savateeva, Diana and Rakovich, Tatsiana and Donegan, John F. and Rakovich, Yury P. and Kelly, Vincent and Lesnyak, Vladimir and Eychmüller, Alexander (2010) CdTe Quantum Dot/Dye Hybrid System as Photosensitizer for Photodynamic Therapy. Nanoscale Research Letters, 5 (4). pp. 753-760. ISSN 1931-7573 (Print) 1556-276X (Online)

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We have studied the photodynamic properties of novel CdTe quantum dots—methylene blue hybrid photosensitizer. Absorption spectroscopy, photoluminescence spectroscopy, and fluorescence lifetime imaging of this system reveal efficient charge transfer between nanocrystals and the methylene blue dye. Near-infrared photoluminescence measurements provide evidence for an increased efficiency of singlet oxygen production by the methylene blue dye. In vitro studies on the growth of HepG2 and HeLa cancerous cells were also performed, they point toward an improvement in the cell kill efficiency for the methylene blue-semiconductor nanocrystals hybrid system.

Item Type:Article
Uncontrolled Keywords:Quantum dots - Nanocrystals - Photosensitiser - Electron transfer - Singlet oxygen
Subjects:Physical Science > Nanophysics
Physical Science > Nanoelectronics
Material Science > Nanochemistry
Physical Science > Photonics
ID Code:8827
Deposited By:IoN
Deposited On:15 Jul 2010 09:47
Last Modified:15 Jul 2010 09:47

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