Nano Archive

Development of Au nanoparticles dispersed carbon nanotube-based biosensor for the detection of paraoxon

Jha, Neetu and Ramaprabhu, Sundara (2010) Development of Au nanoparticles dispersed carbon nanotube-based biosensor for the detection of paraoxon. nanoscale .

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Official URL: http://www.rsc.org/delivery/_ArticleLinking/Displa...

Abstract

A disposable and sensitive biosensor has been fabricated for the detection of the organophosphorous (OP) compound paraoxon using an amperometric technique. For the measurements, gold nanoparticles dispersed on the outer surface of multiwalled carbon nanotubes (Au-MWNTs) has been used as the electrode material, as it possesses high electron transfer rates and provides large immobilization sites for the bioenzymes, which combines with the high electrocatalytic activity of MWNTs for thiocholine oxidation at low potential. Au-MWNTs have been synthesized by chemically reducing Au salt over functionalized MWNTs, and the same has been characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM) and high resolution transmission electron microscopic (HRTEM) techniques. The ability of the Au-MWNTs nanocomposite-based biosensor has been demonstrated to reliably measure the concentration of paraoxon in the nanomolar range.

Item Type:Article
Subjects:Material Science > Nanostructured materials
ID Code:8727
Deposited By:CSMNT
Deposited On:27 Mar 2010 06:13
Last Modified:27 Mar 2010 06:13

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