Nano Archive

Biosynthesis of silver nanoparticles from Staphylococcus aureus and its antimicrobial activity against MRSA and MRSE

Nanda, Anima and Saravanan, M. (2009) Biosynthesis of silver nanoparticles from Staphylococcus aureus and its antimicrobial activity against MRSA and MRSE. Nanomedicine: Nanotechnology, Biology and Medicine, 5 (4). 452 - 456.

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Official URL: http://www.sciencedirect.com/science/article/B7MDB...

Abstract

Silver bionanoparticles (AgNPs) have been known to have inhibitory and bactericidal effects. Resistance to antimicrobial agents by pathogenic bacteria has emerged in recent years and is a major health problem. This report focuses on the synthesis of metallic bionanoparticles of silver using a reduction of aqueous Ag+ ion with the culture supernatants of Staphylococcus aureus. The bioreduction of the Ag+ ions in the solution was monitored in the aqueous component and the spectrum of the solution measured through ultraviolet-visible spectrophotometry and characterized by atomic force microscopy. The AgNPs were evaluated for their antimicrobial activities against different pathogenic organisms. The most sensitive antimicrobial activity has been observed against methicillin-resistant S. aureus followed by methicillin-resistant Staphylococcus epidermidis and Streptococcus pyogenes, whereas only moderate antimicrobial activity was seen against Salmonella typhi and Klebsiella pneumoniae.

Item Type:Article
Uncontrolled Keywords:Bionanoparticles; Staphylococcus aureus; Ultraviolet-visible spectrophotometry; Atomic force microscopy; Antimicrobial activity
Subjects:Biomedical Science > Nanomedicine
ID Code:8585
Deposited By:SPI
Deposited On:25 Mar 2010 22:31
Last Modified:25 Mar 2010 22:31

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