Nano Archive

Mesoporous silica-coated NaYF4:Yb3+, Er3+ particles for drug release

Kong, Deyan and Fan, Yong and Zhang, Cuimiao and Lin, Jun (2010) Mesoporous silica-coated NaYF4:Yb3+, Er3+ particles for drug release. Journal of Nanoparticle Research, 12 (2). pp. 663-673.

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Abstract

NaYF4:Yb3+, Er3+ nanoparticles were successfully prepared by a polyol process using diethyleneglycol (DEG) as solvent. These NaYF4:Yb3+, Er3+ nanoparticles can be coated with mesoporous silica using nonionic triblock copolymer EO20PO70EO20 (P 123) as structure-directing agent and other materials. The composites can load ibuprofen and release the drug in the phosphate buffer solution (PBS). The composites were characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM), nitrogen absorption/desorption isotherms, fluorescence spectra, and UV/Vis absorption spectra, respectively. The composites have the mesoporous structure. In addition, the composites emit red fluorescence (from Er3+) under 980 nm near infrared laser excitation, which can be used as fluorescent probes in the drug-delivery system.

Item Type:Article
Subjects:Physical Science > Nanophysics
Physical Science > Nano objects
Material Science > Nanochemistry
Material Science > Nanostructured materials
Divisions:Faculty of Engineering, Science and Mathematics > School of Physics
Faculty of Engineering, Science and Mathematics > School of Chemistry
ID Code:8211
Deposited By:JNCASR
Deposited On:10 Feb 2010 10:02
Last Modified:10 Feb 2010 10:02

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