Nano Archive

Microtube-based electrode arrays for low invasive extracellular recording with a high signal-to-noise ratio

Takei, Kuniharu and Kawano, Takeshi and Kawashima, Takahiro and Sawada, Kazuaki and Kaneko, Hidekazu and Ishida, Makoto (2010) Microtube-based electrode arrays for low invasive extracellular recording with a high signal-to-noise ratio. BIOMEDICAL MICRODEVICES, 12 (1). pp. 41-48. ISSN 1387-2176 (Print) 1572-8781 (Online)

Full text is not hosted in this archive but may be available via the Official URL, or by requesting a copy from the corresponding author.

Official URL: http://www.springerlink.com/content/r36286n1647u45...

Abstract

We report on the development of a microtube electrode array as a neural interface device. To combine the desired properties for the neural interface device, such as low invasiveness with a small needle and a good signal-to-noise ratio in neural recordings, we applied the structure of a glass pipette electrode to each microtube electrode. The device was fabricated as sub-5-μm-diameter out-of-plane silicon dioxide microtube arrays using silicon microneedle templates, which are grown by the selective vapor–liquid–solid method. The microtubes had inner diameters of 1.9–6.4 µm and a length of 25 µm. Impedances ranged from 220 kΩ to 1.55 MΩ, which are less than those for conventional microneedles. In addition, the microtube electrodes had less signal attenuation than conventional microneedle electrodes. We confirmed that the effects of parasitic capacitances between neighboring microtubes and channels were sufficiently small using a test signal. Finally, neural responses evoked from a rat peripheral nerve were recorded in vivo using a microtube electrode to confirm that this type of electrode can be used for both electrophysiological measurements and as a neural interface device.

Item Type:Article
Subjects:Biomedical Science > Nanobiotechnology
Physical Science > Nanoelectronics
ID Code:8188
Deposited By:M T V
Deposited On:12 Feb 2010 14:05
Last Modified:12 Feb 2010 14:05

Repository Staff Only: item control page