Vetrone, Fiorenzo and Naccache, Rafik and Juarranz de la Fuente, Angeles and Sanz-Rodríguez, Francisco and Blazquez-Castro, Alfonso and Rodriguez, Emma Martin and Jaque, Daniel and Solé, José García and Capobianco, John A. (2009) Intracellular imaging of HeLa cells by non-functionalized NaYF4 : Er3+, Yb3+ upconverting nanoparticles. nanoscale .
Full text is not hosted in this archive but may be available via the Official URL, or by requesting a copy from the corresponding author.
Official URL: http://www.rsc.org/delivery/_ArticleLinking/Displa...
Abstract
We report on the efficient incorporation of non-functionalized NaYF4 : Er3+, Yb3+ nanoparticles inside HeLa live cancer cells by direct endocytosis. The efficient two-photon excited near-infrared-to-visible upconversion fluorescence of these nanoparticles is then used to obtain high-contrast intracellular fluorescence images of single cells. These images reveal a redistribution of the nanoparticles inside the cell as the incubation time increases. Thus, non-functionalized NaYF4 : Er3+, Yb3+ nanoparticles emerge as very promising fluorescence probes for real-time imaging of cellular dynamics.
| Item Type: | Article |
|---|---|
| Subjects: | Biomedical Science > Nanobiotechnology |
| ID Code: | 7858 |
| Deposited By: | CSMNT |
| Deposited On: | 27 Nov 2009 16:21 |
| Last Modified: | 27 Nov 2009 16:21 |
Repository Staff Only: item control page
