Liu, Xinyu and Sun, Yu (2009) Microfabricated glass devices for rapid single cell immobilization in mouse zygote microinjection. BIOMEDICAL MICRODEVICES, 11 (6). pp. 1169-1174. ISSN 1387-2176 (Print) 1572-8781 (Online)
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Official URL: http://www.springerlink.com/content/r7324h63370817...
This paper presents the design and microfabrication of a vacuum-based cell holding device for single-cell immobilization and the use of the device in mouse zygote microinjection. The device contains many through-holes, constructed via two-sided glass wet etching and polydimethylsiloxane (PDMS)-glass bonding. Experimental results of mouse zygote immobilization and microinjection demonstrate that the device is effective for rapid cell immobilization and does not produce negative effect on embryonic development.
|Subjects:||Biomedical Science > Nanobiotechnology|
|Deposited By:||M T V|
|Deposited On:||30 Nov 2009 13:00|
|Last Modified:||30 Nov 2009 13:00|
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