Beznosov, S. and Pyatibratov, M. and Fedorov, O. (2009) Archaeal flagella as matrices for new nanomaterials. Nanotechnologies in Russia, 4 . pp. 373-378.
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Official URL: http://dx.doi.org/10.1134/S1995078009050164
Archaeal flagella are among the most perspective biopolymer structures for use in nanotechnology and have certain advantages over both bacterial analogues and viral particles. Such advantages include their resistance to dissociating agents and their adhesion properties to certain types of surfaces. As a rule, archaeal flagella consist of several protein subunit types (flagellins). This allows multifunctional filaments to be designed with each flagellin differently modified. One of the reasons that archaeal flagella have not been used in nanotechnology is the lack of data about the spatial structure of subunits in flagella. We present an experimental approach for determining flagellin molecule sites which are exposed on the flagellum surface and suitable for directed insertion of groups capable of binding certain ligands. It was shown that modified flagella of halophilic archaea Halobacterium salinarum can be used as scaffolds for designing nowel nanomaterials.
|Deposited By:||Prof. Alexey Ivanov|
|Deposited On:||11 Nov 2009 07:53|
|Last Modified:||11 Nov 2009 08:00|
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