Nano Archive

Small-Angle Neutron Scattering for Molecular Biology: Basics and Instrumentation

Heller, William T (2009) Small-Angle Neutron Scattering for Molecular Biology: Basics and Instrumentation. Micro and Nano Technologies in Bioanalysis, 544 . ISSN 1064-3745 (Print) 1940-6029 (Online) (In Press)

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Abstract

As researchers strive to understand the interplay between the complex molecular systems that make up living cells, tools for characterizing the interactions between the various players involved have developed. Small-angle neutron scattering (SANS) plays an important role in building a molecular-level understanding of the structures of macromolecular systems that make up cells. SANS is widely applicable to the study of biological structures including, but by no means limited to, protein–protein or protein–nucleic acid complexes, lipid membranes, cellular scaffolding, and amyloid plaques. Here, we present a brief description of the technique as it is commonly applied to the study of biological systems and an overview instrumentation that is available at the various facilities around the world.

Item Type:Article
Uncontrolled Keywords:Small-angle Small-angle scattering - Neutrons - Contrast variation - User facilities
Subjects:Material Science > Bio materials
ID Code:7202
Deposited By:CSMNT
Deposited On:30 Sep 2009 08:35
Last Modified:12 Nov 2009 16:21

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