Nano Archive

Nano-titanium dioxide enhanced biosensing of the interaction of dacarbazine with DNA and DNA bases

Song, Min and Zhang, Renyun and Wang, Xuemei (2006) Nano-titanium dioxide enhanced biosensing of the interaction of dacarbazine with DNA and DNA bases. Materials Letters, 60 (17-18). 2143 - 2147.

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Official URL: http://www.sciencedirect.com/science/article/B6TX9...

Abstract

The biomolecular binding behavior of anticancer drug dacarbazine (DTIC) in the presence of titanium dioxide (TiO2) nanoparticle interface has been studied by using electrochemical methods. The results indicate that the presence of TiO2 nanoparticles can obviously increase the binding affinity of DTIC to DNA or DNA bases and significantly enhance the detection sensitivity for the relative biomolecular recognition.

Item Type:Article
Uncontrolled Keywords:DNA
Subjects:Analytical Science > Nanotechnology for sensing and actuating
Material Science > Nanostructured materials
ID Code:6796
Deposited By:SPI
Deposited On:18 Jan 2010 10:02
Last Modified:18 Jan 2010 10:02

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