Nano Archive

Silicon nitride nanoparticles for surface-assisted laser desorption/ionization of small molecules

Shariatgorji, Mohammadreza and Amini, Nahid and Ilag, Leopold L. (2009) Silicon nitride nanoparticles for surface-assisted laser desorption/ionization of small molecules. Journal of Nanoparticle Research, 11 (6). pp. 1509-1512.

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Official URL: http://www.springerlink.com/content/878p212v829001...

Abstract

Conventional matrix-assisted laser desorption/ionization mass spectrometry is limited to analyses of higher molecular weight compounds due to high background noise generated by the matrix in the lower mass region. Surface-assisted laser desorption/ionization (SALDI) mass spectrometry is an alternative solution to this problem. Nanoparticles, structured silicon surfaces and carbon allotropes are commonly used as SALDI surfaces. Here, for the first time, we demonstrate the application of silicon nitride nanoparticles as a suitable medium for laser desorption/ionization of small drug molecules.

Item Type:Article
Uncontrolled Keywords:Silicon nitride nanoparticles - Surface-assisted laser desorption/ionization mass spectrometry - Small molecules
Subjects:Biomedical Science > Nanomedicine
ID Code:6548
Deposited By:SPI
Deposited On:27 Jul 2009 15:52
Last Modified:27 Jul 2009 15:52

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