Shariatgorji, Mohammadreza and Amini, Nahid and Ilag, Leopold L. (2009) Silicon nitride nanoparticles for surface-assisted laser desorption/ionization of small molecules. Journal of Nanoparticle Research, 11 (6). pp. 1509-1512.
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Official URL: http://www.springerlink.com/content/878p212v829001...
Conventional matrix-assisted laser desorption/ionization mass spectrometry is limited to analyses of higher molecular weight compounds due to high background noise generated by the matrix in the lower mass region. Surface-assisted laser desorption/ionization (SALDI) mass spectrometry is an alternative solution to this problem. Nanoparticles, structured silicon surfaces and carbon allotropes are commonly used as SALDI surfaces. Here, for the first time, we demonstrate the application of silicon nitride nanoparticles as a suitable medium for laser desorption/ionization of small drug molecules.
|Uncontrolled Keywords:||Silicon nitride nanoparticles - Surface-assisted laser desorption/ionization mass spectrometry - Small molecules|
|Subjects:||Biomedical Science > Nanomedicine|
|Deposited On:||27 Jul 2009 15:52|
|Last Modified:||27 Jul 2009 15:52|
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