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A biological porin engineered into a molecular, nanofluidic diode

Miedema, Henk and Vrouenraets, Maarten and Wierenga, Jenny and Meijberg, Wirn and Robillard, George and Eisenberg, Bob (2007) A biological porin engineered into a molecular, nanofluidic diode. NANO LETTERS, 7 (9). pp. 2886-2891.

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Official URL: http://pubs.acs.org/doi/abs/10.1021/nl0716808

Abstract

We changed the nonrectifying biological porin OmpF into a nanofluidic diode. To that end, we engineered a pore that possesses two spatially separated selectivity filters of opposite charge where either cations or anions accumulate. The observed current inhibition under applied reverse bias voltage reflects, we believe, the creation of a zone depleted of charge carriers, in a sense very similar to what happens at the np junction of a semiconductor device.

Item Type:Article
Subjects:Biomedical Science > Nanobiotechnology
ID Code:6242
Deposited By:IoN
Deposited On:12 Aug 2009 16:55
Last Modified:12 Aug 2009 16:55

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