Nano Archive

High throughput quantification of protein expression of cancer antigens in tissue microarray using quantum dot nanocrystals

Ghazani, Arezou A. and Lee, Jeongjin A. and Klostranec, Jesse and Xiang, Qing and Dacosta, Ralph S. and Wilson, Brian C. and Tsao, Ming S. and Chan, Warren C. W. (2006) High throughput quantification of protein expression of cancer antigens in tissue microarray using quantum dot nanocrystals. NANO LETTERS, 6 (12). pp. 2881-2886.

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Abstract

We developed and validated a novel method for quantifying protein expression of cancer tumors in an accurate, sensitive, and high throughput format. This technique integrates quantum dots, tissue microarray, optical spectroscopy, and algorithm design for analysis of tumor biopsies. The integration of this method for tissue analysis in the clinic bears potential impact for improving the diagnosis and treatment of cancer.

Item Type:Article
Subjects:Biomedical Science > Nanobiotechnology
Biomedical Science > Nanotechnology for human health
Biomedical Science > Nanomedicine
ID Code:6199
Deposited By:IoN
Deposited On:10 Sep 2009 10:10
Last Modified:10 Sep 2009 10:10

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