Nano Archive

DNA-based aromatic zipper fastened by an aromatic stacking interaction

Kubota, Mio and Ono, Akira (2004) DNA-based aromatic zipper fastened by an aromatic stacking interaction. Tetrahedron Letters, 45 (29). 5755 - 5758.

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Official URL: http://www.sciencedirect.com/science/article/B6THS...

Abstract

A novel thymidine–methyl red conjugate was synthesized and incorporated into oligodeoxyribonucleotides (ODNs). The ODNs containing the conjugate formed a novel nucleic acid-based structural motif, the aromatic zipper, which fastens via the stacking interactions of aromatic residues that are attached to DNA strands. The aromatic zipper can be used to stabilize structural motifs in nucleic acids and their analogues, such as hairpin structures, by fastening their ends. A novel nucleic acid-based structural motif, the aromatic zipper, which fastens via the stacking interactions of aromatic residues that are attached to DNA strands, was created. The aromatic zipper can be used to stabilize structural motifs in nucleic acids and their analogues, such as hairpin structures, by fastening their ends.

Item Type:Article
Uncontrolled Keywords: Aromatic zipper; Molecular architecture; Super molecule; Aromatic stacking; Bio-nano materials
Subjects:Material Science > Bio materials
Biomedical Science > Nanomedicine
ID Code:5791
Deposited By:SPI
Deposited On:23 Jul 2009 15:58
Last Modified:23 Jul 2009 15:58

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