Kubota, Mio and Ono, Akira (2004) DNA-based aromatic zipper fastened by an aromatic stacking interaction. Tetrahedron Letters, 45 (29). 5755 - 5758.
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Official URL: http://www.sciencedirect.com/science/article/B6THS...
Abstract
A novel thymidine–methyl red conjugate was synthesized and incorporated into oligodeoxyribonucleotides (ODNs). The ODNs containing the conjugate formed a novel nucleic acid-based structural motif, the aromatic zipper, which fastens via the stacking interactions of aromatic residues that are attached to DNA strands. The aromatic zipper can be used to stabilize structural motifs in nucleic acids and their analogues, such as hairpin structures, by fastening their ends. A novel nucleic acid-based structural motif, the aromatic zipper, which fastens via the stacking interactions of aromatic residues that are attached to DNA strands, was created. The aromatic zipper can be used to stabilize structural motifs in nucleic acids and their analogues, such as hairpin structures, by fastening their ends.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Aromatic zipper; Molecular architecture; Super molecule; Aromatic stacking; Bio-nano materials |
| Subjects: | Material Science > Bio materials Biomedical Science > Nanomedicine |
| ID Code: | 5791 |
| Deposited By: | SPI |
| Deposited On: | 23 Jul 2009 15:58 |
| Last Modified: | 23 Jul 2009 15:58 |
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