Gabelica, Valérie and Pauw, Edwin De and Karas, Michael (2004) Influence of the capillary temperature and the source pressure on the internal energy distribution of electrosprayed ions. International Journal of Mass Spectrometry, 231 (2-3). 189 - 195.
Full text is not hosted in this archive but may be available via the Official URL, or by requesting a copy from the corresponding author.
Official URL: http://www.sciencedirect.com/science/article/B6VND...
The internal energy distributions in a heated capillary nano-electrospray source have been determined using the “survival yield” method. At low capillary temperatures, the internal energy distribution is characterized by a low-energy tail, which can be attributed to a fraction of ions not fully desolvated in the heated capillary. This low-energy tais is shown to disappear when the source pressure is increased. This explains why increased source pressure is favorable in the case of highly hydrophilic compounds or non-covalent complexes in order to achieve sufficient desolvation without fragmentation. It is also shown that “high temperature-low voltage” are not equivalent to “low temperature-high voltage” source conditions. These observations are important for fundamental issues as well as for source-CID mass spectral library searching applications.
|Additional Information:||Special Issue: In honour of Jean-Claude Tabet|
|Uncontrolled Keywords:||Electrospray; Internal energy; Heated capillary; Pressure effect|
|Subjects:||Biomedical Science > Nanomedicine|
|Deposited On:||24 Jul 2009 09:18|
|Last Modified:||24 Jul 2009 09:18|
Repository Staff Only: item control page