Nano Archive

Peptide-based fibrous biomaterials: some things old, new and borrowed

Woolfson, Derek N. and Ryadnov, Maxim G. (2006) Peptide-based fibrous biomaterials: some things old, new and borrowed. Current Opinion in Chemical Biology, 10 (6). 559 - 567.

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Official URL: http://www.sciencedirect.com/science/article/B6VRX...

Abstract

Bioinspired fibrous materials that span the nano-to-meso scales have potentially broad applications in nanobiotechnology; for instance, as scaffolds in 3D cell culture and tissue engineering, and as templates for the assembly of other polymer and inorganic materials. The field is burgeoning, and this review is necessarily focused. It centres on recent developments in the design of peptide-based fibres and particularly those using the α-helix and the collagen triple helix as building blocks for self-assembly. Advances include new designs in both categories, the assembly of more-complex topologies using fibres themselves as building blocks, and the decoration of the assembled materials with functional moieties.

Item Type:Article
Additional Information:Model systems / Biopolymers
Subjects:Biomedical Science > Nanobiotechnology
ID Code:5742
Deposited By:SPI
Deposited On:24 Jul 2009 15:04
Last Modified:24 Jul 2009 15:04

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