Nano Archive

Subcellular Localization of Thiol-Capped CdTe Quantum Dots in Living Cells

Zhang, Yu and Mi, Lan and Xiong, Rongling and Wang, Pei-Nan and Chen, Ji-Yao and Yang, Wuli and Wang, Changchun and Peng, Qian (2009) Subcellular Localization of Thiol-Capped CdTe Quantum Dots in Living Cells. Nanoscale Research Letters, 4 (7). pp. 606-612.


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Internalization and dynamic subcellular distribution of thiol-capped CdTe quantum dots (QDs) in living cells were studied by means of laser scanning confocal microscopy. These unfunctionalized QDs were well internalized into human hepatocellular carcinoma and rat basophilic leukemia cells in vitro. Co-localizations of QDs with lysosomes and Golgi complexes were observed, indicating that in addition to the well-known endosome-lysosome endocytosis pathway, the Golgi complex is also a main destination of the endocytosed QDs. The movement of the endocytosed QDs toward the Golgi complex in the perinuclear region of the cell was demonstrated.

Item Type:Article
Subjects:Physical Science > Nano objects
Biomedical Science > Nanoscale biological processes
Physical Science > Quantum phenomena
ID Code:5540
Deposited By:IoN
Deposited On:30 Jun 2009 11:26
Last Modified:30 Jun 2009 11:26

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