Nano Archive

Nanostructured Biomaterials with Controlled Properties Synthesis and Characterization

Teodor, Eugenia and Lit¸escu, Simona Carmen and Petcu, C. and Mihalache, Mihaela and Somoghi, Raluca (2009) Nanostructured Biomaterials with Controlled Properties Synthesis and Characterization. Nanoscale Research Letters, 4 (6). pp. 544-549.

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Official URL: http://www.springerlink.com/content/n3715664966374...

Abstract

Magnetic nanoparticles were obtained using an adjusted Massart method and were covered in a layer-by-layer technique with hydrogel-type biocompatible shells, from chitosan and hyaluronic acid. The synthesized nanocomposites were characterized using dynamic light scattering, transmission electron microscopy, and Fourier transformed infrared spectroscopy. Biocompatibility of magnetic nanostructures was determined by MTT (3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide) cell proliferation assay, swelling tests, and degradation tests. In addition, interaction of hydrogel-magnetic nanoparticles with microorganisms was studied. The possibility of precise nanoparticles size control, as long as the availability of bio-compatible covering, makes them suitable for biomedical applications.

Item Type:Article
Subjects:Physical Science > Nanomagnetics
Material Science > Bio materials
Biomedical Science > Nanomedicine
Divisions:Faculty of Engineering, Science and Mathematics > School of Geography
Faculty of Engineering, Science and Mathematics > School of Electronics and Computer Science
Faculty of Engineering, Science and Mathematics > School of Engineering Sciences
Faculty of Engineering, Science and Mathematics > School of Civil Engineering and the Environment
Faculty of Engineering, Science and Mathematics > School of Chemistry
ID Code:5524
Deposited By:IoN
Deposited On:22 May 2009 16:12
Last Modified:22 May 2009 16:12

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