Nano Archive

Single particle adsorbing transfer system

Woide, Daniela and Mayer, Veronika and Wachtmeister, Thorsten and Hoehn, Norbert and Zink, Albert and Koehler, Udo and Thalhammer, Stefan (2009) Single particle adsorbing transfer system. Biomedical Microdevices, 11 (3). pp. 609-614.

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Here we present a novel approach for horizontal transfer of single particles after laser microdissection. The developed technique is a single particle adsorbing system for highly selective and gentle horizontal transfer of microdissected fixed and living material. As mediated via low-pressure technology, the transfer process can be precisely controlled, thus facilitating horizontal particle transfer of any isolated material, e.g. tissue material, single cells or chromosomes, in addition to precise positioning for sample release. This collection method allows one to predefine target positions and enables material transfer without contamination to any planar microchip device. This contamination free transfer is indispensable for novel lab-on-a-chip systems performing nanoscale polymerase chain reaction analyses. Using virtual reaction chamber microdevices, small amounts of microdissected material—as little as one single cell—can be directly transmitted and immediately used for single cell analysis.

Item Type:Article
Subjects:Analytical Science > Nanotechnology for sensing and actuating
Biomedical Science > Nanoscale biological processes
ID Code:5498
Deposited By:IoN
Deposited On:29 Jun 2009 14:10
Last Modified:29 Jun 2009 14:10

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