Nano Archive

Nano-liter size droplet dispenser using electrostatic manipulation technique

Choi, Wan-Kyu and Lebrasseur, Eric and Al-Haq, Muhammad Imran and Tsuchiya, Hidenori and Torii, Toru and Yamazaki, Hiroki and Shinohara, Etsuo and Higuchi, Toshiro (2007) Nano-liter size droplet dispenser using electrostatic manipulation technique. Sensors and Actuators A: Physical, 136 (1). 484 - 490.

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Official URL: http://www.sciencedirect.com/science/article/B6THG...

Abstract

A new dispenser made of Teflon that uses electrostatic manipulation technique to dispense nano-liter size droplets based on the electrostatic actuation mechanism has been developed. Two types of dispensers were developed, viz. a single-hole type (Teflon tube) and a multiple-hole dispenser (Teflon block). The single-hole type dispenser successfully dispensed droplets of a solution supplied by a syringe pump on an electrode panel surface; and thus the droplets become available for subsequent manipulation on the electrode panel. Based on the same principle, a compact Teflon block dispenser was designed that can simultaneously dispense five different solutions in a small area (30 mm). The size of dispensed droplets can be controlled by various factors, e.g., flow rate of solution, dispensing height, applied voltage, frequency of voltage pattern. We could dispense the droplets in the range of 55–210 ± 8 nL. This technique can be applied for automation of repetitive pipetting and screening operations in protein crystallization.

Item Type:Article
Additional Information:25th Anniversary of Sensors and Actuators A: Physical
Uncontrolled Keywords:Droplet dispenser; Electrostatic manipulation; Protein crystallization; Teflon block-dispenser
Subjects:Analytical Science > Nanotechnology for sensing and actuating
Analytical Science > Metrology and standards in nanotechnology
ID Code:4859
Deposited By:SPI
Deposited On:24 Apr 2009 17:59
Last Modified:24 Apr 2009 17:59

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