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Development of a direct three-dimensional biomicrofabrication concept based on electrospraying a custom made siloxane sol

Sullivan, Alice C. and Jayasinghe, Suwan N. (2007) Development of a direct three-dimensional biomicrofabrication concept based on electrospraying a custom made siloxane sol. BIOMICROFLUIDICS, 1 (3).

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Official URL: http://link.aip.org/link/?BIOMGB/1/34103/1

Abstract

We demonstrate here the discovery of a unique and direct three-dimensional biomicrofabrication concept possessing the ability to revolutionize the jet-based fabrication arena. Previous work carried out on similar jet-based approaches have been successful in fabricating only vertical wall/pillar-structures by the controlled deposition of stacked droplets. However, these advanced jet-techniques have not been able to directly fabricate self-supporting arches/links (without molds or reaction methods) between adjacent structures (walls or pillars). Our work reported here gives birth to a unique type of jet determined by high intensity electric fields, which is derived from a specially formulated siloxane sol. The sol studied here has been chosen for its attractive properties (such as an excellent cross-linking nature as well as the ability to polymerize via polycondensation on deposition to its biocompatability), which promotes direct forming of biostructures with nanometer (< 50 nm) sized droplets in three dimensions. We foresee that this direct three-dimensional biomicrofabrication jet technique coupled with a variety of formulated sols having focused and enhanced functionality will be explored throughout the physical and life sciences. (c) 2007 American Institute of Physics.

Item Type:Article
Subjects:Material Science > Nanofabrication processes and tools
Biomedical Science > Nanobiotechnology
Material Science > Nanostructured materials
ID Code:485
Deposited By:INVALID USER
Deposited On:04 Dec 2008 14:44
Last Modified:04 Dec 2008 14:44

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