Nano Archive

Microfluidic large-scale integration on a chip for mass production of monodisperse droplets and particles

Nisisako, Takasi and Torii, T. (2008) Microfluidic large-scale integration on a chip for mass production of monodisperse droplets and particles. LAB ON A CHIP, 8 (2). pp. 287-293.

Full text is not hosted in this archive but may be available via the Official URL, or by requesting a copy from the corresponding author.

Official URL: http://www.rsc.org/publishing/journals/LC/article....

Abstract

In this study, we report the mass production of monodisperse emulsion droplets and particles using microfluidic large-scale integration on a chip. The production module comprises a glass microfluidic chip with planar microfabricated 16-256 droplet-formation units (DFUs) and a palm-sized stainless steel holder having several layers for supplying liquids into the inlets of the mounted chip. By using a module having 128 cross-junctions (i.e., 256 DFUs) arranged circularly on a 4 cm 6 4 cm chip, we could produce droplets of photopolymerizable acrylate monomer at a throughput of 320.0 mL h(-1). The product was monodisperse, having a mean diameter of 96.4 mm, with a coefficient of variation (CV) of 1.3%. Subsequent UV polymerization off the module yielded monodisperse acrylic microspheres at a throughput of similar to 0.3 kg h(-1). Another module having 128 co-flow geometries could produce biphasic Janus droplets of black and white segments at 128.0 mL h(-1). The product had a mean diameter of 142.3 mm, with a CV of 3.3%. This co-flow module could also be applied in the mass production of homogeneous monomer droplets.

Item Type:Article
Subjects:Material Science > Nanofabrication processes and tools
Material Science > Nanochemistry
ID Code:475
Deposited By:INVALID USER
Deposited On:04 Dec 2008 15:47
Last Modified:05 Jan 2009 17:23

Repository Staff Only: item control page