Brehm, Markus and Taubner, Thomas and Hillenbrand, Rainer and Keilmann, Fritz (2006) Infrared spectroscopic mapping of single nanoparticles and viruses at nanoscale resolution. NANO LETTERS, 6 (7). pp. 1307-1310.
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Official URL: http://pubs.acs.org/doi/abs/10.1021/nl0610836
We demonstrate that scattering near-field microscopy (s-SNOM) can determine infrared ``fingerprint'' spectra of individual poly( methyl methacrylate) nanobeads and viruses as small as 18 nm. Amplitude and phase spectra are found surprisingly strong, even at a probed volume of only 10(-20) l, and robust in regard to particle size and substrate. This makes infrared spectroscopic s-SNOM a versatile tool for chemical and-in the case of protein-secondary-structure identification.
|Subjects:||Analytical Science > Microscopy and probe methods|
Biomedical Science > Nanobiotechnology
|Deposited By:||Farnush Anwar|
|Deposited On:||22 Jan 2009 13:36|
|Last Modified:||29 Jan 2009 11:57|
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