Nano Archive

Isolation of discrete nanoparticle - DNA conjugates for plasmonic applications

Claridge, Shelley A. and Liang, Huiyang W. and Basu, S. Roger and Frechet, Jean M. J. and Alivisatos, A. Paul (2008) Isolation of discrete nanoparticle - DNA conjugates for plasmonic applications. NANO LETTERS, 8 (4). pp. 1202-1206.

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Discrete DNA-gold nanoparticle conjugates with DNA lengths as short as 15 bases for both 5 and 20 nm gold particles have been purified by anion-exchange HPLC. Conjugates comprising short DNA (<40 bases) and large gold particles (>= 20 nm) are difficult to purify by other means and are potential substrates for plasmon coupling experiments. Conjugate purity is demonstrated by hybridizing complementary conjugates to form discrete structures, which are visualized by TEM.

Item Type:Article
Subjects:Biomedical Science > Nanobiotechnology
Material Science > Bio materials
Material Science > Nanostructured materials
ID Code:3282
Deposited By:Farnush Anwar
Deposited On:15 Jan 2009 15:26
Last Modified:28 Jan 2009 16:06

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