Nano Archive

Gold-silica nanocomposites for the detection of human ovarian cancer cells: a preliminary study

Mishra, Y. K. and Mohapatra, S. and Avasthi, D. K. and Kabiraj, D. and Lalla, N. P. and Pivin, J. C. and Sharma, Himani and Kar, Rajarshi and Singh, Neeta (2007) Gold-silica nanocomposites for the detection of human ovarian cancer cells: a preliminary study. NANOTECHNOLOGY, 18 (34).

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Official URL: http://dx.doi.org/10.1088/0957-4484/18/34/345606

Abstract

We report the structural and optical properties of Au nanoparticles embedded in a silica matrix synthesized by atom beam co-sputtering. The presence of surface plasmon resonant absorption indicates the formation of Au nanoparticles. Transmission electron microscopy (TEM) studies show the presence of Au nanoparticles with an average size ranging from similar to 1.8 to 5.4 nm with narrow size distributions depending on the relative areas of Au and SiO2. We discuss the process of nucleation and growth of Au nanoparticles in the nanocomposite films formed by co-sputtering. The present method of nanoparticle synthesis is compared with other ion beam based techniques such as ion implantation and ion beam mixing. Preliminary experiments for the detection of human ovarian cancer cells using these Au nanoparticles are described.

Item Type:Article
Subjects:Analytical Science > Microscopy and probe methods
Biomedical Science > Nanotechnology for human health
Biomedical Science > Nanomedicine
ID Code:3264
Deposited By:Farnush Anwar
Deposited On:15 Jan 2009 15:47
Last Modified:15 Jan 2009 15:47

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