Nano Archive

DNA nucleoside interaction and identification with carbon nanotubes

Meng, Sheng and Maragakis, Paul and Papaloukas, Costas and Kaxiras, Efthimios (2006) DNA nucleoside interaction and identification with carbon nanotubes. NANO LETTERS, 7 (1). pp. 45-50.

Full text is not hosted in this archive but may be available via the Official URL, or by requesting a copy from the corresponding author.

Official URL: http://pubs.acs.org/doi/abs/10.1021/nl0619103

Abstract

We investigate the interaction of individual DNA nucleosides with a carbon nanotube (CNT) in vacuum and in the presence of external gate voltage. We propose a scheme to discriminate between nucleosides on CNTs based on measurement of electronic features through a local probe such as scanning tunneling spectroscopy. We demonstrate through quantum mechanical calculations that these measurements can achieve 100% efficiency in identifying DNA bases. Our results support the practicality of ultrafast DNA sequencing using electrical measurements.

Item Type:Article
Subjects:Analytical Science > Nanotechnology for sensing and actuating
Physical Science > Nano objects
Biomedical Science > Nanotechnology for human health
ID Code:3199
Deposited By:Anuj Seth
Deposited On:26 May 2009 11:31
Last Modified:26 May 2009 11:31

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