Nano Archive

Length-dependent uptake of DNA-wrapped single-walled carbon nanotubes

Becker, Matthew L. and Fagan, Jeffrey A. and Gallant, Nathan D. and Bauer, Barry J. and Bajpai, Vardan and Hobbie, Erik K. and Lacerda, Silvia H. and Migler, Kalman B. and Jakupciak, John P. (2007) Length-dependent uptake of DNA-wrapped single-walled carbon nanotubes. ADVANCED MATERIALS, 19 (7). pp. 939-945.

Full text is not hosted in this archive but may be available via the Official URL, or by requesting a copy from the corresponding author.

Official URL: http://www3.interscience.wiley.com/journal/1141900...

Abstract

A length threshold for cell uptake of DNA-wrapped single-walled carbon nanotubes (SWNTs) by human lung fibroblasts (IMR90) is identified. Competitive uptake experiments with well-defined and characterized length fractions show that SWNTs above the length threshold are excluded from the cell, whereas SWNTs labeled with Cy3-derivatized DNA below the threshold are able to access the cell interior, as shown in the fluorescence image and on the cover.

Item Type:Article
Subjects:Physical Science > Nano objects
Biomedical Science > Nanotechnology for human health
NanoSafety > Environment, health and safety aspects of nanotechnology
ID Code:3157
Deposited By:Anuj Seth
Deposited On:26 May 2009 13:42
Last Modified:26 May 2009 13:42

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