Balani, Kantesh and Anderson, Rebecca and Laha, Tapas and Andara, Melanie and Tercero, Jorge and Crumpler, Eric and Agarwal, Arvind (2007) Plasma-sprayed carbon nanotube reinforced hydroxyapatite coatings and their interaction with human osteoblasts in vitro. BIOMATERIALS, 28 (4). pp. 618-624.
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Official URL: http://dx.doi.org/10.1016/j.biomaterials.2006.09.0...
Carbon nanotubes (CNT) possess excellent mechanical properties to play the role as reinforcement for imparting strength and toughness to brittle hydroxyapatite (HA) bioceramic coating. However, lack of processing technique to uniformly distribute multiwalled CNTs in HA coating and limited studies and sparse knowledge evincing toxicity of CNTs has kept researchers in dispute for long. In the current work, we have addressed these issues by (i) successfully distributing multiwalled CNT reinforcement in HA coating using plasma spraying to improve the fracture toughness (by 56%) and enhance crystallinity (by 27%), and (ii) culturing human osteoblast hFOB 1.19 cells onto CNT reinforced HA coating to elicit its biocompatibility with living cells. Unrestricted growth of human ostcoblast hFOB 1.19 cells has been observed near CNT regions claiming assistance by CNT surfaces to promote cell growth and proliferation. (c) 2006 Elsevier Ltd. All rights reserved.
|Uncontrolled Keywords:||hydroxyapatite coating; carbon nanotube (CNT); plasma spraying; titanium alloy; crystallinity; human osteoblast|
|Subjects:||Material Science > Nanofabrication processes and tools|
Physical Science > Nano objects
Biomedical Science > Nanoscale biological processes
Material Science > Nanostructured materials
|Deposited By:||Anuj Seth|
|Deposited On:||13 Jan 2009 13:25|
|Last Modified:||20 Jan 2009 14:57|
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