Nano Archive

Can apomyoglobin form a complex with a spherical ligand? Interactions between apomyoglobin and [C-60] fullerene derivative

Kolsenik, Jenny and Belgorodsky, Bogdan and Fadeev, Ludmila and Gozin, Michael (2007) Can apomyoglobin form a complex with a spherical ligand? Interactions between apomyoglobin and [C-60] fullerene derivative. JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY, 7 (4-5). pp. 1389-1394.

Full text is not hosted in this archive but may be available via the Official URL, or by requesting a copy from the corresponding author.

Official URL: http://www.ingentaconnect.com/asp/jnn/2007/0000000...

Abstract

The preparation and characterization of the stable equine skeletal muscle apomyoglobin and eee-isomer of tris-malonic acid [C-60] fullerene complex is reported. For this new bio-nanomaterial preparation, a procedure of complexation-during-protein-refolding was used and the obtained compound sustained separation by gel-filtration and ion-exchange chromatography. The apomyoglobin-tris-malonic acid [C-60] fullerene complex was characterized by UV-vis spectroscopy, steady state fluorescence, time-resolved fluorescence, and circular dichroism spectroscopies. Important information provided by this study, regarding the stability and properties of new material, may lead to a better understanding of the apomyoglobin protein binding characteristics, as well as to development of novel antioxidant and photodynamic therapeutic agents and components for bioelectronic devices.

Item Type:Article
Uncontrolled Keywords:apomyoglobin; [C-60]fullerene; complex
Subjects:Biomedical Science > Nanobiotechnology
Material Science > Bio materials
ID Code:2911
Deposited By:Farnush Anwar
Deposited On:13 Jan 2009 12:22
Last Modified:26 Jan 2009 16:07

Repository Staff Only: item control page