Koch, Manuela and Schmid, Franziska F-F and Zoete, Vincent and Meuwly, Markus (2006) Insulin: a model system for nanomedicine? NANOMEDICINE, 1 (3). pp. 373-378.
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Official URL: http://www.futuremedicine.com/doi/abs/10.2217/1743...
One of the predominant aims of insulin therapy for diabetes is to appropriately mimic physiological insulin secretion levels and their correlation with glucose concentration in healthy individuals. This report outlines current methods and their limitations in glycemic control and their possible relationship to insufficient knowledge about the structure and dynamics of the insulin hormone itself. Based on recent experimental and computational work, a possible approach to less-invasive insulin administration is sketched.
|Uncontrolled Keywords:||insulin analog; insulin dimer; nanomedicine; pharmacokinetics|
|Subjects:||Biomedical Science > Nanotechnology for human health|
Biomedical Science > Nanomedicine
|Deposited By:||Farnush Anwar|
|Deposited On:||09 Jan 2009 12:09|
|Last Modified:||13 Jan 2009 17:12|
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