Nano Archive

Investigation into the antibacterial behaviour of suspensions of ZnO nanoparticles (ZnO nanofluids)

Zhang, Lingling and Jiang, Yunhong and Ding, Yulong and Povey, Malcolm and York, David (2007) Investigation into the antibacterial behaviour of suspensions of ZnO nanoparticles (ZnO nanofluids). JOURNAL OF NANOPARTICLE RESEARCH, 9 (3). pp. 479-489.

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The antibacterial behaviour of suspensions of zinc oxide nanoparticles (ZnO nanofluids) against E. Coli has been investigated. ZnO nanoparticles from two sources are used to formulate nanofluids. The effects of particle size, concentration and the use of dispersants on the antibacterial behaviour are examined. The results show that the ZnO nanofluids have bacteriostatic activity against E. coli. The antibacterial activity increases with increasing nanoparticle concentration and increases with decreasing particle size. Particle concentration is observed to be more important than particle size under the conditions of this work. The results also show that the use of two types of dispersants (Polyethylene Glycol (PEG) and Polyvinylpyrolidone (PVP)) does not affect much the antibacterial activity of ZnO nanofluids but enhances the stability of the suspensions. SEM analyses of the bacteria before and after treatment with ZnO nanofluids show that the presence of ZnO nanoparticles damages the membrane wall of the bacteria. Electrochemical measurements using a model DOPC monolayer suggest some direct interaction between ZnO nanoparticles and the bacteria membrane at high ZnO concentrations.

Item Type:Article
Uncontrolled Keywords:antibacterial activity; zinc oxide nanoparticles; nanofluids; mechanisms; E. coli; nanoengineering
Subjects:Physical Science > Nano objects
Biomedical Science > Nanobiotechnology
Biomedical Science > Nanotechnology for animal health
Biomedical Science > Nanotechnology for human health
Material Science > Nanochemistry
ID Code:2640
Deposited By:Anuj Seth
Deposited On:27 May 2009 12:23
Last Modified:27 May 2009 12:23

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