Nano Archive

One-step, nanoparticle-mediated bacterial detection with magnetic relaxation

Kaittanis, Charalambos and Naser, Saleh A. and Perez, J. Manuel (2007) One-step, nanoparticle-mediated bacterial detection with magnetic relaxation. NANO LETTERS, 7 (2). pp. 380-383.

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Official URL: http://dx.doi.org/10.1021/nl062553z

Abstract

Acknowledging the need for the development of fast and sensitive bacterial detection methods, we functionalized superparamagnetic iron oxide nanoparticles to identify Mycobacterium avium spp. paratuberculosis (MAP), through magnetic relaxation. Our results indicate that the MAP nanoprobes (1) bind specifically to MAP, (2) can quantify the bacterial target quickly in milk and blood with high sensitivity, and (3) are not susceptible to interferences caused by other bacteria. The use of the described magnetic nanosensors in the identification and quantification of bacteria in clinical and environmental samples is anticipated.

Item Type:Article
Subjects:Physical Science > Nanophysics
Physical Science > Nano objects
Analytical Science > Nanotechnology for sensing and actuating
Biomedical Science > Nanobiotechnology
ID Code:2621
Deposited By:Anuj Seth
Deposited On:09 Jan 2009 15:17
Last Modified:20 Jan 2009 11:28

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