Nano Archive

Mimicking cellular environments by nanostructured soft interfaces

Graeter, Stefan V. and Huang, Jinghuan and Perschmann, Nadine and Lopez-Garcia, Monica and Kessler, Horst and Ding, Jiandong and Spatz, Joachim P. (2007) Mimicking cellular environments by nanostructured soft interfaces. NANO LETTERS, 7 (5). pp. 1413-1418. ISSN 1530-6984

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We present herein an innovative technique for decorating soft polymer surfaces with metallic nanostructures fabricated by diblock copolymer micelle nanolithography. Thus far, such nanolithography has been limited to plasma-resistant inorganic substrates such as glass. Our new development is based on the transfer of nanopatterns from glass to soft substrates. Special emphasis is given to hydrogel surfaces with respect to their properties for tailoring cell adhesion. Besides planar surfaces, periodic gold nanopatterns on curved surfaces have been fabricated, as demonstrated on the interior surface of a tubelike hydrogel, which potentially mimic situations of vessels in vivo.

Item Type:Article
Subjects:Biomedical Science > Nanobiotechnology
ID Code:2185
Deposited By:M T V
Deposited On:22 Dec 2008 15:55
Last Modified:22 Dec 2008 15:55

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