Nano Archive

Spontaneous stretching of DNA in a two-dimensional nanoslit

Krishnan, Madhavi and Moench, Ingolf and Schwille, Petra (2007) Spontaneous stretching of DNA in a two-dimensional nanoslit. NANO LETTERS, 7 (5). pp. 1270-1275. ISSN 1530-6984

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Official URL: http://pubs.acs.org/doi/abs/10.1021/nl0701861

Abstract

DNA molecules in silicon dioxide-glass fluidic nanoslits spontaneously extend at the lateral sidewalls of the slit. The nanoslit geometry, however, physically confines polymer molecules to two spatial dimensions; further reduction in configurational entropy resulting in axially stretched molecules arises spontaneously and appears to be electrostatically mediated. The observations not only shed light on electrostatic interactions of charged soft matter with like-charged confining walls but also offer a new method to stretch DNA in solution.

Item Type:Article
Subjects:Biomedical Science > Nanobiotechnology
ID Code:2178
Deposited By:M T V
Deposited On:24 Dec 2008 15:03
Last Modified:24 Dec 2008 15:03

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