Nano Archive

In-situ synthesis of poly(dimethylsiloxane)-gold nanoparticles composite films and its application in microfluidic systems

Zhang, Qing and Xu, Jing-Juan and Liu, Yan and Chen, Hong-Yuan (2008) In-situ synthesis of poly(dimethylsiloxane)-gold nanoparticles composite films and its application in microfluidic systems. LAB ON A CHIP, 8 (2). pp. 352-357.

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Official URL: http://www.rsc.org/publishing/journals/LC/article....

Abstract

We presented a simple approach for in-situ synthesis of poly(dimethylsiloxane) (PDMS)-gold nanoparticles composite film based on the special characteristics of PDMS itself. It is an environmentally safe synthesis method without the requirement of additional reducing/stabilizing agents. The region where the resulting gold nanoparticles distribute (in the matrix or on the surface of the polymer) and the size of the nanoparticles, as well as the colour of the free-standing films, can be simply controlled by adjusting the ratio of curing agent and the PDMS monomer. The chemical and optical properties of these composite films were studied. Using such a method, gold nanoparticle micropatterns on PDMS surfaces can be performed. And based on the gold nanoparticles micropattern, further modification with antibodies, antigens, enzymes and other biomolecules can be achieved. To verify this ability, an immobilized glucose oxidase (GOx) reactor in microchannels was built and its performance was studied. The experiments have shown that the resulting composite film may have a lot of potential merits in protein immobilization, immunoassays and other biochemical analysis on PDMS microchips.

Item Type:Article
Subjects:Material Science > Functional and hybrid materials
Material Science > Nanofabrication processes and tools
Biomedical Science > Nanobiotechnology
ID Code:1294
Deposited By:Anuj Seth
Deposited On:15 Dec 2008 12:42
Last Modified:20 Jan 2009 09:51

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