Nano Archive

Hyperbranched poly(amidoamine) as the stabilizer and reductant to prepare colloid silver nanoparticles in situ and their antibacterial activity

Zhang, Yongwen and Peng, Huashong and Huang, Wei and Zhou, Yongfeng and Zhang, Xuehong and Yan, Deyue (2008) Hyperbranched poly(amidoamine) as the stabilizer and reductant to prepare colloid silver nanoparticles in situ and their antibacterial activity. JOURNAL OF PHYSICAL CHEMISTRY C, 112 (7). pp. 2330-2336.

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Official URL: http://dx.doi.org/10.1021/jp075436g

Abstract

This study provided a facile and green method to prepare stable colloid silver nanoparticles in aqueous solution by utilizing the amine-terminated hyperbranched poly(amidoamine) (HPAMAM-NH2) as both stabilizer and reductant. The formation of silver nanoparticles was verified by FTIR, UV-vis, TEM, EDS, and XRD measurements. Monodispersed colloid silver nanoparticles with small particle sizes were obtained, and the average particle size could be effectively controlled from ca. 15 to 4 nm by simply adjusting the molar ratio of N/Ag in feed. The antibacterial activity of the HPAMAM-NH2/Ag nanocomposites was also investigated against Gram-positive and Gram-negative bacteria. They were able to efficiently inhibit the growth and multiplication of several bacteria, including Staphylococcus aureus, Bacillus subtilis, Escherichia coli, and Klebsiella mobilis, and the bacterial inhibition ratio reached up to 95% at a low silver concentration of 2.7 mu g/mL.

Item Type:Article
Subjects:Material Science > Nanofabrication processes and tools
Physical Science > Nano objects
Biomedical Science > Nanobiotechnology
Material Science > Nanochemistry
Biomedical Science > Nanomedicine
ID Code:1285
Deposited By:Anuj Seth
Deposited On:15 Dec 2008 13:17
Last Modified:20 Jan 2009 09:52

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