Nano Archive

Gold nanoparticle based FRET for DNA detection

Ray, Paresh Chandra and Darbha, Gopala Krishna and Ray, Anandhi and Walker, Joshua and Hardy, William (2007) Gold nanoparticle based FRET for DNA detection. PLASMONICS, 2 (4). pp. 173-183.

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The nanoscience revolution that sprouted throughout the 1990s is having great impact in current and future DNA detection technology around the world. In this review, we report our recent progress on gold nanoparticle based fluorescence resonance energy transfer assay to monitor DNA hybridization as well as the cleavage of DNA by nucleases. We tried to discuss a reasonable account of the science and the important fundamental work carried out in this area. We also report the development of a compact, highly specific, inexpensive and user-friendly optical fiber laser-induced fluorescence sensor based on fluorescence quenching by nanoparticles to detect single-strand DNA hybridization at femtomolar level.

Item Type:Article
Subjects:Analytical Science > Microscopy and probe methods
Analytical Science > Nanotechnology for sensing and actuating
Physical Science > Nano objects
Biomedical Science > Nanobiotechnology
ID Code:1258
Deposited By:Anuj Seth
Deposited On:15 Dec 2008 15:25
Last Modified:20 Jan 2009 09:57

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