Sun, Nijuan and McMullan, Martin and Papakonstantinou, Pagona and Gao, Hui and Zhang, Xinxiang and Mihailovic, Dragan and Li, Meixian (2008) Bioassembled nanocircuits of Mo6S9-xIx nanowires for electrochemical immunodetection of estrone hapten. ANALYTICAL CHEMISTRY, 80 (10). pp. 3593-3597.
Full text is not hosted in this archive but may be available via the Official URL, or by requesting a copy from the corresponding author.
Official URL: http://dx.doi.org/10.1021/ac7024893
Abstract
We demonstrate a novel and highly sensitive electrochemical detection of estrone based on an immunosensor platform, composed of bioassembled nanocircuits of Mo6S9-xIx nanowires (MoSI NWs) covalently connected to anti-estrone antibodies. The one-step, label-free, and quantitative detection of estrone is realized by employing the [Ru(NH3)(6)](3+/2+) redox ions to sense anti-estrone antibody and estrone interactions. The MoSI NWs/anti-estrone antibody nanocircuit architectures provide an amplification and conductive pathway for the specific electrochemical sensing of estrone hapten. A detection limit of 1.4 pg.mL(-1) was achieved in contrast to previous electrochemical techniques in which the sensitivity was limited to the nanomolar range.
| Item Type: | Article |
|---|---|
| Subjects: | Analytical Science > Nanotechnology for sensing and actuating Biomedical Science > Nanobiotechnology Material Science > Nanochemistry |
| ID Code: | 1236 |
| Deposited By: | Anuj Seth |
| Deposited On: | 16 Dec 2008 09:55 |
| Last Modified: | 19 Jan 2009 11:22 |
Repository Staff Only: item control page
