Li, Bo and Shang, Lu and Marcus, Matthew S. and Clare, Tarni Lasseter and Perkins, Edward and Hamers, Robert J. (2008) Chemoselective nanowire fuses: Chemically induced cleavage and electrical, detection of carbon nanofiber bridges. SMALL, 4 (6). pp. 795-801.
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Official URL: http://www3.interscience.wiley.com/journal/1198164...
A new type of nanoscale bioswitch based on the electrical detection of chemically induced cleavage of chemical bonds, which bind individual nanowires across a pair of electrodes is demonstrated. Carbon nanofibers are manipulated using dielectrophoresis to form single-nanowire bridges across microelectrode junctions, and are anchored through a biomolecular interaction. Once in place, chemically induced cleavage of a recognition site along the bonds linking the nanowire to the electrodes allows the nanowire to be easily removed by a flow of fluid; this removal can be detected in real time via changes in the AC electrical response. This form of sensing is inherently digital in nature as the removal of a single nanowire produces a sudden decrease in the current between electrodes and is essentially a chemoselective fuse. These results suggest that this sensing principle could be a general method for digital chemical and/or biological sensing using individual nanowires.
|Uncontrolled Keywords:||biosensors; disulfides; molecular recognition; nanoelectronics; switches|
|Subjects:||Analytical Science > Nanotechnology for sensing and actuating|
Physical Science > Nanoelectronics
Biomedical Science > Nanobiotechnology
Material Science > Nanostructured materials
|Deposited By:||Anuj Seth|
|Deposited On:||16 Dec 2008 11:20|
|Last Modified:||19 Jan 2009 11:41|
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