Reddy, Ravikiran K. and Bothara, Manish G. and Barrett, Thomas W. and Carruthers, John and Prasad, Shalini (2008) Nanomonitors: Protein biosensors for rapid analyte analysis. IEEE SENSORS JOURNAL, 8 (5-6). pp. 720-723.
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Abstract
A technology for electrical detection of proteins has been developed using electrical conductance measurements. It is based on developing high density, low-volume multiwell plate devices. The scientific core of this technology lies in integrating nanoporous membranes with. microfabricated chip platforms. This results in the conversion of individual pores into wells of picoliter volume. Specific antibodies are localized and isolated into individual wells. The formation of the antibody-antigen binding complex occurs in individual wells. The membrane allows for robust separation among individual wells. This technology has the capability to achieve near real-time detection with improved sensitivity and selectivity.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | cardiac markers; clinical diagnostics; conductance measurements; electrical protein sensor |
| Subjects: | Analytical Science > Nanotechnology for sensing and actuating Biomedical Science > Nanobiotechnology Material Science > Nanochemistry Material Science > Nanostructured materials |
| ID Code: | 1209 |
| Deposited By: | Anuj Seth |
| Deposited On: | 16 Dec 2008 13:52 |
| Last Modified: | 18 Feb 2009 17:55 |
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