Wang, Ronghui and Ruan, Chuanmin and Kanayeva, Damira and Lassiter, Kentu and Li, Yanbin (2008) TiO2 nanowire bundle microelectrode based impedance immunosensor for rapid and sensitive detection of Listeria monocytogenes. NANO LETTERS, 8 (9). pp. 2625-2631.
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Official URL: http://dx.doi.org/10.1021/nl080366q
A novel TiO2 nanowire bundle microelectrode based immunosensor was demonstrated as a more sensitive, specific, and rapid technology for detection of Listeria monocytogenes. TiO2 nanowire bundle was prepared through a hydrothermal reaction of alkali with TiO2 powder and connected to gold microelectrodes with mask welding. Monoclonal antibodies were immobilized on the surface of a TiO2 nanowire bundle to specifically capture L. monocytogenes. Impedance change caused by the nanowire-antibody-bacteria complex was measured and correlated to bacterial number. This nanowire bundle based immunosensor could detect as low as 10(2) cfu/ml of L. monocytogenes in 1 h without significant interference from other foodborne pathogens.
|Subjects:||Analytical Science > Nanotechnology for sensing and actuating|
Biomedical Science > Nanobiotechnology
Material Science > Nanostructured materials
|Deposited By:||Anuj Seth|
|Deposited On:||16 Dec 2008 14:12|
|Last Modified:||19 Jan 2009 12:05|
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