Chang, Shu-quan and Kang, Bin and Dai, Yao-dong and Zhang, Hong-xu and Chen, Da (2011) One-step fabrication of biocompatible chitosan-coated ZnS and ZnS:Mn2+ quantum dots via a Î³-radiation route. NANOSCALE RESEARCH LETTERS, 6 (1). pp. 1-7. ISSN 1931-7573 (Print) 1556-276X (Online)
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Official URL: http://www.nanoscalereslett.com/content/6/1/591
Biocompatible chitosan-coated ZnS quantum dots [CS-ZnS QDs] and chitosan-coated ZnS:Mn2+ quantum dots [CS-ZnS:Mn2+ QDs] were successfully fabricated via a convenient one-step Î³-radiation route. The as-obtained QDs were around 5 nm in diameter with excellent water-solubility. These QDs emitting strong visible blue or orange light under UV excitation were successfully used as labels for PANC-1 cells. The cell experiments revealed that CS-ZnS and CS-ZnS:Mn2+ QDs showed low cytotoxicity and good biocompatibility, which offered possibilities for further biomedical applications. Moreover, this convenient synthesis strategy could be extended to fabricate other nanoparticles coated with chitosan.
|Subjects:||Material Science > Nanofabrication processes and tools|
|Deposited By:||M T V|
|Deposited On:||05 Jan 2012 10:39|
|Last Modified:||05 Jan 2012 10:39|
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