Nano Archive

One-step fabrication of biocompatible chitosan-coated ZnS and ZnS:Mn2+ quantum dots via a γ-radiation route

Chang, Shu-quan and Kang, Bin and Dai, Yao-dong and Zhang, Hong-xu and Chen, Da (2011) One-step fabrication of biocompatible chitosan-coated ZnS and ZnS:Mn2+ quantum dots via a γ-radiation route. NANOSCALE RESEARCH LETTERS, 6 (1). pp. 1-7. ISSN 1931-7573 (Print) 1556-276X (Online)

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Official URL: http://www.nanoscalereslett.com/content/6/1/591

Abstract

Biocompatible chitosan-coated ZnS quantum dots [CS-ZnS QDs] and chitosan-coated ZnS:Mn2+ quantum dots [CS-ZnS:Mn2+ QDs] were successfully fabricated via a convenient one-step γ-radiation route. The as-obtained QDs were around 5 nm in diameter with excellent water-solubility. These QDs emitting strong visible blue or orange light under UV excitation were successfully used as labels for PANC-1 cells. The cell experiments revealed that CS-ZnS and CS-ZnS:Mn2+ QDs showed low cytotoxicity and good biocompatibility, which offered possibilities for further biomedical applications. Moreover, this convenient synthesis strategy could be extended to fabricate other nanoparticles coated with chitosan.

Item Type:Article
Subjects:Material Science > Nanofabrication processes and tools
ID Code:11585
Deposited By:M T V
Deposited On:05 Jan 2012 10:39
Last Modified:05 Jan 2012 10:39

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