Govindaraju, K. and Tamilselvan, S. and Kiruthiga, V. and Singaravelu, G. (2011) Silvernanotherapy on the viral borne disease of silkworm Bombyx mori L. Journal of Nanoparticle Research, 13 (12). pp. 6377-6388.
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Antiviral assays of chemically and biologically synthesized silver nanoparticles were made against BmNPV (Bombyx mori Nuclear Polyhedrosis Virus). Reduction of silver ions by sodium citrate and Spirulina platensis led to the formation of spherical silver nanoparticles of 40â60 and 7â16Â nm size. Single cell protein (Spirulina platensis)-synthesized silver nanoparticles showed the strongest antiviral activity. Immunological studies made on the silkworm Bombyx mori disclosed that a significant increase in the total hemocyte count and differential hemocyte count due to S. platensis-synthesized silver nanoparticles supplementation. Improvement in the defense mechanism was noticed from the strengthened peritrophic membrane of the digestive tract and the increased total protein. Overall, the results presented illustrate that single cell protein-synthesized silver nanoparticles supplementation is effective in controlling viral-borne diseases of the silkworm.
|Deposited By:||Prof. Alexey Ivanov|
|Deposited On:||05 Jan 2012 09:30|
|Last Modified:||05 Jan 2012 09:42|
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