Nano Archive

Gold nanoparticle induced conformational changes in heme protein

Sahoo, Dibakar and Bhattacharya, Prosenjit and Patra, Hirak Kumar and Mandal, Paulami and Chakravorti, Sankar (2011) Gold nanoparticle induced conformational changes in heme protein. Journal of Nanoparticle Research, 13 (12). pp. 6755-6760.

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Abstract

Change of α-helical structure of heme protein (Hb) to a β-sheet and random coil conformation because of the interaction of glycine capped gold nanoparticles (20–60 nm) as observed from attenuation total reflectance, absorption, Fourier transform infra red, and Circular Dichroism spectroscopy has been reported in this article. Upon interaction, protein takes a cylindrical shape of length 12 μm and diameter 0.35 μm as revealed from scanning electron microscopy and transmission electron microscopy. The Selected-Area Electron beam Diffraction pattern shows change of crystalline structure in GNP to amorphous nature with the interaction of Hb.

Item Type:Article
ID Code:11451
Deposited By:Prof. Alexey Ivanov
Deposited On:05 Jan 2012 09:29
Last Modified:05 Jan 2012 09:42

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